Pathologic Predictors of Renal Outcome and Therapeutic Efficacy in IgA Nephropathy: Validation of the Oxford Classification
نویسندگان
چکیده
منابع مشابه
Pathologic predictors of renal outcome and therapeutic efficacy in IgA nephropathy: validation of the oxford classification.
BACKGROUND AND OBJECTIVES The Oxford classification of IgA nephropathy (IgAN) may aid in predicting prognosis and providing therapeutic strategy but must be validated in different ancestry. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS A total of 410 patients with IgAN, enrolled from one of the largest renal centers in China, were evaluated for the predictive value of the Oxford classificatio...
متن کاملValidating the oxford classification of IgA nephropathy.
The evolution of patients with IgA nephropathy (IgAN) varies greatly, and predictive tools are needed to assess confidently the risk for progression. Although in many studies clinical risk factors such as hypertension and proteinuria have consistently been linked to outcome, the independent value of pathology remains debated. Pathologists have developed a number of classifications over the year...
متن کاملValidation of the Oxford classification of IgA nephropathy in cohorts with different presentations and treatments
The Oxford Classification of IgA Nephropathy (IgAN) identified mesangial hypercellularity (M), endocapillary proliferation (E), segmental glomerulosclerosis (S), and tubular atrophy/interstitial fibrosis (T) as independent predictors of outcome. Whether it applies to individuals excluded from the original study and how therapy influences the predictive value of pathology remain uncertain. The V...
متن کاملThe Oxford Classification predictors of chronic kidney disease in pediatric patients with IgA nephropathy.
OBJECTIVE The Oxford Classification for Immunoglobulin A nephropathy (IgAN) identifies pathological variables that may predict the decline of renal function. This study aimed to evaluate the Oxford Classification variables as predictors of renal dysfunction in a cohort of Brazilian children and adolescents with IgAN. METHODS A total of 54 patients with IgAN biopsied from 1982 to 2010 were ass...
متن کاملValidation of the Oxford Classification of IgA Nephropathy: A Single-Center Study in Korean Adults
BACKGROUND/AIMS The recently published Oxford classification of IgA nephropathy (IgAN) proposed a split system for histological grading, based on prognostic pathological features. This new classification system must be validated in a variety of cohorts. We investigated whether these pathological features were applicable to an adult Korean population. METHODS In total, 69 adult Korean patients...
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ژورنال
عنوان ژورنال: Clinical Journal of the American Society of Nephrology
سال: 2011
ISSN: 1555-9041,1555-905X
DOI: 10.2215/cjn.11521210